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et al.) (Cambridge Univ

A B12 deficiency can happen due to age, low absorption, low IF levels, or diet

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Residual gastric content from dinner slows absorption, and circadian NNMT activity peaks in the evening mean the enzyme has already processed most of the days nicotinamide load

Methylation happens when nutrients such as Folic Acid, Vitamin B6 and Vitamin B12 donate a methyl group (a molecule combo of one carbon and three hydrogen), and transfer it to a protein, enzyme, hormone or right onto DNA